SCHEMBL9153530

SCHEMBL9153530

Cc1cccc(C(C)(C)NC=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ACHE P22303 1/20 0.39
GAA P10253 1/20 0.38
KIF11 P52732 5/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KCNH2 Q12809 1/20 0.36
HPGD P15428 1/20 0.36
PTPN5 P54829 1/20 0.35
KCNK3 O14649 2/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21303793 0.88 GAA (0.46) ACHEGAAHTTHDAC8HDAC6
SCHEMBL18533529 0.80 GAA (0.41) ACHEGAACYP2C19HDAC8
SCHEMBL9153494 0.79 KIF11 (0.40) LMNAGAAKIF11MEN1KMT2A
SCHEMBL1911380 0.78 HDAC3 (0.41) KMT2ACYP2C19HDAC8HDAC6
SCHEMBL27012754 0.78 ACHE (0.48) LMNAACHEGAAKIF11MEN1
SCHEMBL20193400 0.77 GAA (0.39) GAA
SCHEMBL13811887 0.77 TP53 (0.43) LMNAGAAMEN1KMT2ACYP2D6
SCHEMBL10066565 0.76 TSHR (0.46) LMNAACHEGAAMEN1KMT2A
SCHEMBL11627278 0.76 GAA (0.38) LMNAACHEGAAMEN1KMT2A
SCHEMBL19941003 0.76 GAA (0.38) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5434119-A TRANSPORT RECORDING LAYER COMPRISING DEVELOPER FORMED BY BLOCKING HYDROXYL GROUP WITH DEVELOPING FUNCTION JUJO PAPER CO., LTD. (JP) 1995-07-18 US disclosed
EP-0520404-A1 Transparent recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1992-12-30 EP disclosed