Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154194 | 0.90 | MEN1 (0.50) | KMT2ALMNAL3MBTL1GAAMEN1 | |
| SCHEMBL9158114 | 0.86 | KMT2A (0.50) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4008681 | 0.82 | HPGD (0.56) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4008336 | 0.82 | HPGD (0.59) | ALDH1A1POLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL4518662 | 0.82 | ROCK2 (0.47) | ALDH1A1POLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL9158053 | 0.81 | HPGD (0.51) | ALDH1A1POLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL9157966 | 0.80 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8860050 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2NPC1TP53 | |
| SCHEMBL3847252 | 0.79 | MEN1 (0.58) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13102343 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |