Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596007 | 0.88 | GRIN1 (0.55) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9596003 | 0.88 | GRIN1 (0.55) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| SCHEMBL10435467 | 0.82 | LMNA (0.52) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10435271 | 0.81 | LMNA (0.51) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10435270 | 0.81 | LMNA (0.51) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9603447 | 0.79 | LMNA (0.59) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9603446 | 0.79 | LMNA (0.59) | GRIN1GRIN2BLMNAKDM4EALDH1A1 | |
| SCHEMBL5056593 | 0.77 | CYP3A4 (0.54) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL22281477 | 0.77 | CYP3A4 (0.54) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10435262 | 0.76 | LMNA (0.61) | LMNAKDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7188172-A | — | — | None | — | — | JP | disclosed |
| JP-H07188172-A | PYRIDINECARBOXIMIDAMIDE COMPOUND AND ITS USE | KIRIN BREWERY CO LTD | 1995-07-25 | — | — | JP | disclosed |