Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603446 | 1.00 | LMNA (0.59) | LMNAALDH1A1HTTEPHX2CYP2C9 | |
| SCHEMBL10435262 | 0.85 | LMNA (0.61) | LMNAALDH1A1HTTEPHX2CYP2C9 | |
| SCHEMBL10435263 | 0.85 | LMNA (0.61) | LMNAALDH1A1HTTEPHX2CYP2C9 | |
| SCHEMBL9153569 | 0.79 | GRIN1 (0.71) | LMNAALDH1A1HTTEPHX2KDM4E | |
| SCHEMBL9217826 | 0.77 | EPHX2 (0.50) | LMNAEPHX2CYP2C9CYP2C19TBXAS1 | |
| SCHEMBL9215256 | 0.77 | EPHX2 (0.50) | LMNAEPHX2CYP2C9CYP2C19TBXAS1 | |
| SCHEMBL10435468 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1HTTEPHX2CYP2C9 | |
| SCHEMBL10435469 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1HTTEPHX2CYP2C9 | |
| SCHEMBL5056593 | 0.75 | CYP3A4 (0.54) | LMNAALDH1A1HTTCYP2C9CYP2C19 | |
| SCHEMBL22281477 | 0.75 | CYP3A4 (0.54) | LMNAALDH1A1HTTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |