Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153602 | 0.83 | KMT2A (0.53) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL9157003 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9155385 | 0.75 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9154000 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MAPK1KMT2AMEN1LMNA | |
| SCHEMBL9153991 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MAPK1KMT2AMEN1LMNA | |
| SCHEMBL9158335 | 0.73 | MEN1 (0.44) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL5292795 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1KMT2AMEN1CYP3A4 | |
| SCHEMBL9158466 | 0.72 | MEN1 (0.49) | ALDH1A1MAPK1NPSR1KMT2AMEN1 | |
| SCHEMBL9152819 | 0.72 | TSHR (0.60) | MAPTALDH1A1MAPK1NPSR1KMT2A | |
| SCHEMBL9155455 | 0.72 | NPSR1 (0.42) | MAPTALDH1A1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |