Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154000 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL5292795 | 0.82 | ALDH1A1 (0.61) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL9156271 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNAGAATP53 | |
| SCHEMBL9156264 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNAGAATP53 | |
| SCHEMBL8860020 | 0.75 | ALDH1A1 (0.55) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL9157809 | 0.75 | ALDH1A1 (0.62) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL9155385 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL9153616 | 0.73 | MAPT (0.58) | ALDH1A1POLBKMT2AMEN1LMNA | |
| SCHEMBL29398039 | 0.73 | L3MBTL1 (0.63) | ALDH1A1POLBCA12CA9KMT2A | |
| SCHEMBL6318634 | 0.72 | POLB (0.49) | ALDH1A1POLBCA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |