SCHEMBL915381

SCHEMBL915381

CCOP(=O)(O)Nc1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
MAPT P10636 1/20 0.46
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
GAA P10253 2/20 0.43
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL914682 0.87 NPSR1 (0.67) NPSR1MAPTKMT2AMEN1ALDH1A1
SCHEMBL9328075 0.82 NPSR1 (0.76) NPSR1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL9328047 0.81 NPSR1 (0.73) NPSR1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL9407022 0.81 NPSR1 (0.73) NPSR1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL9407017 0.73 NPSR1 (0.61) NPSR1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL915097 0.73 MMP2 (0.46) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL914714 0.73 NPC1 (0.48) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL914602 0.71 PPARD (0.42) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL16868444 0.71 NPSR1 (0.58) NPSR1MAPTKMT2AMEN1ALDH1A1
SCHEMBL10192180 0.71 NPSR1 (0.69) NPSR1MAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed