SCHEMBL9154

SCHEMBL9154

COc1[c]ccc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20875253 0.82 NFE2L2 (0.36)
SCHEMBL3144092 0.79 PDGFRB (0.43)
SCHEMBL28130967 0.78 PTPN1 (0.31)
SCHEMBL6191317 0.78 ABCB1 (0.35)
SCHEMBL3143778 0.78 PDGFRB (0.37)
SCHEMBL160927 0.77 NQO1 (0.34)
SCHEMBL162720 0.77
SCHEMBL28051257 0.77
SCHEMBL13722453 0.77 SQOR (0.32)
SCHEMBL4858324 0.76 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118368986-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2024-07-19 CN claimed
CN-118339167-A Microbiocidal bicyclic heterocyclic derivatives 先正达农作物保护股份公司 2024-07-12 CN claimed
EP-4380933-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-06-12 EP claimed
CN-118055930-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2024-05-17 CN claimed
EP-4346411-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-04-10 EP claimed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN claimed
WO-2024068947-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 WO claimed
WO-2024068950-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 WO claimed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
CN-117769551-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2024-03-26 CN claimed
CN-1206589-A Process for preparing medicine composition WYETH JOHN & BROTHER LTD (GB) 1999-02-03 CN claimed
EP-0708085-A2 Antiviral ethers of aspartate protease substrate isosteres CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
EP-0512755-B1 Piperazine derivatives WYETH JOHN & BROTHER LTD (GB) 1994-12-14 EP claimed
US-5164400-A Enzyme inhibitors, anticholesterol, antilipemic FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-11-17 US claimed
EP-0512755-A2 Piperazine derivatives JOHN WYETH &amp; BROTHER LIMITED (GB) 1992-11-11 EP claimed
EP-0414023-A2 Pyrroloquinoline compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-02-27 EP claimed
EP-0097425-B1 FUNGICIDAL OR PLANT GROWTH REGULATING TRIAZOLYL ETHANOLS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-08 EP claimed
EP-0048548-B1 PHARMACEUTICAL COMPOSITIONS OF FUNGICIDAL TRIAZOLE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP claimed
EP-0097425-A2 Fungicidal or plant growth regulating triazolyl ethanols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-04 EP claimed
EP-0048548-A1 Pharmaceutical compositions of fungicidal triazole derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-31 EP claimed