Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.65 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247382 | 0.87 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13701464 | 0.86 | SLC6A3 (0.63) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL14390374 | 0.86 | SLC6A3 (0.63) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3554782 | 0.86 | SLC6A3 (0.72) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4206472 | 0.85 | SLC6A3 (0.65) | SLC6A3HTR1ES1PR3SLC6A2SLC6A4 | |
| SCHEMBL4950911 | 0.84 | SLC6A3 (0.63) | SLC6A3HTR1ES1PR3SLC6A2SLC6A4 | |
| SCHEMBL517226 | 0.83 | HTR1E (0.49) | SLC6A3HTR1ES1PR3SLC6A2 | |
| SCHEMBL12871836 | 0.83 | HTR1E (0.49) | SLC6A3HTR1ES1PR3SLC6A2 | |
| SCHEMBL4245494 | 0.82 | SLC6A3 (0.61) | SLC6A3HTR1ES1PR3SLC6A2SLC6A4 | |
| SCHEMBL10006263 | 0.82 | SLC6A3 (0.59) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414008-A | Hypotensive and antiatherosclerotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |