Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154447 | 1.00 | CYP2C19 (0.56) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9425599 | 0.99 | CYP2C19 (0.55) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9426303 | 0.99 | CYP2C19 (0.55) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9159457 | 0.91 | CYP2C19 (0.54) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9156987 | 0.89 | ALDH1A1 (0.55) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9426464 | 0.88 | ALDH1A1 (0.55) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9426160 | 0.88 | ALDH1A1 (0.55) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9426250 | 0.87 | ALDH1A1 (0.53) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9426638 | 0.86 | CYP2C19 (0.49) | CYP2C19ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9426634 | 0.86 | CYP2C19 (0.49) | CYP2C19ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533516-B1 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0533516-A2 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |