Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9426160 | 0.99 | ALDH1A1 (0.55) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9426873 | 0.94 | ITGB3 (0.51) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9426241 | 0.93 | MEN1 (0.49) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9158857 | 0.92 | P2RX7 (0.53) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9426464 | 0.92 | ALDH1A1 (0.55) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9426250 | 0.91 | ALDH1A1 (0.53) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9154136 | 0.89 | CYP2C19 (0.56) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9154447 | 0.89 | CYP2C19 (0.56) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9154438 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTCYP2C19MEN1KMT2A | |
| SCHEMBL9425893 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTCYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533516-B1 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0533516-A2 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |