SCHEMBL9154339

SCHEMBL9154339

Cc1cc(-c2ccc(C)c(C(=O)O)c2)ccc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 4/20 0.62
RXRB P28702 2/20 0.62
RXRA P19793 1/20 0.60
RARB P10826 6/20 0.54
RARA P10276 5/20 0.52
RARG P13631 5/20 0.52
KDM4E B2RXH2 1/20 0.48
GFER P55789 1/20 0.48
KMT2A Q03164 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
CFD P00746 1/20 0.46
HNF4A P41235 2/20 0.44
ACMSD Q8TDX5 2/20 0.44
DHFR P00374 1/20 0.44
PTGER4 P35408 1/20 0.44
ALDH1A1 P00352 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9154099 0.98 MCL1 (0.61) MCL1RXRBRXRARARBRARA
SCHEMBL70164 0.92 MCL1 (0.66) MCL1RXRBRXRARARBKDM4E
SCHEMBL1498034 0.92 RXRB (0.70) MCL1RXRBRXRARARBRARA
SCHEMBL29771992 0.92 RXRB (0.70) MCL1RXRBRXRARARBRARA
Hydrochloric Acid SCHEMBL9150803 0.90 RXRB (0.68) MCL1RXRBRXRARARBRARA
Hydrochloric Acid SCHEMBL4365452 0.90 RXRB (0.68) MCL1RXRBRXRARARBRARA
Hydrochloric Acid SCHEMBL9153007 0.90 MCL1 (0.63) MCL1RXRBRXRARARBRARA
SCHEMBL17177748 0.88 RXRB (0.71) MCL1RXRBRXRARARBRARA
SCHEMBL9149082 0.86 MCL1 (0.53) MCL1RXRBRXRARARBRARA
SCHEMBL8840571 0.84 MCL1 (0.65) MCL1RXRBRXRARARBHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7173270-A None JP disclosed
JP-3077843-A None JP disclosed
JP-6041284-A None JP disclosed
JP-6220188-A None JP disclosed
JP-7207005-A None JP disclosed
JP-4081425-A None JP disclosed
JP-6157755-A None JP disclosed
JP-H07207005-A AROMATIC COPOLYESTER UBE IND LTD 1995-08-08 JP disclosed
JP-H07173270-A AROMATIC COPOLYESTER UBE IND LTD 1995-07-11 JP disclosed
EP-0439616-B1 METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS UBE INDUSTRIES (JP) 1995-01-04 EP disclosed
JP-H06220188-A AROMATIC COPOLYETER AMIDE UBE IND LTD 1994-08-09 JP disclosed
JP-H06157755-A AROMATIC COPOLYESTER IMIDE UBE IND LTD 1994-06-07 JP disclosed
JP-H0641284-A AROMATIC COPOLYESTER UBE IND LTD 1994-02-15 JP disclosed
US-5243067-A Oxidative coupling UBE INDUSTRIES, LTD. (JP) 1993-09-07 US disclosed
US-5118782-A THERMOTROPIC AROMATIC POLYESTER WHICH IS MELT-PROCESSABLE AT LOW TEMPERATURES AND EXHIBITS LIQUID CRYSTALLINE PROPERTIES UBE INDUSTRIES, LTD. (JP) 1992-06-02 US disclosed
JP-H0481425-A AROMATIC COPOLYESTER UBE IND LTD 1992-03-16 JP disclosed
EP-0439616-A1 METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS UBE INDUSTRIES, LTD. (JP) 1991-08-07 EP disclosed
JP-H0377843-A PRODUCTION OF BIPHENYL COMPOUND AND NOVEL BIPHENYL COMPOUND UBE IND LTD 1991-04-03 JP disclosed
EP-0417651-A2 Thermotropic aromatic polyester UBE INDUSTRIES, LTD. (JP) 1991-03-20 EP disclosed