Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154475 | 1.00 | HDAC1 (0.57) | HDAC1HDAC2MAOAMAOBHDAC3 | |
| SCHEMBL10723135 | 1.00 | HDAC1 (0.57) | HDAC1HDAC2MAOAMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL3981565 | 0.98 | HDAC1 (0.55) | HDAC1HDAC2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL3981568 | 0.98 | HDAC1 (0.55) | HDAC1HDAC2MAOAMAOB | |
| SCHEMBL8574266 | 0.79 | HDAC1 (0.59) | HDAC1HDAC2MAOAMAOB | |
| SCHEMBL11207094 | 0.79 | HDAC1 (0.55) | HDAC1HDAC2MAOAMAOBHDAC3 | |
| SCHEMBL16787362 | 0.77 | ATM (0.45) | HDAC1HDAC2MAOAMAOBHDAC3 | |
| SCHEMBL2291836 | 0.77 | ATM (0.45) | HDAC1HDAC2MAOAMAOBHDAC3 | |
| SCHEMBL9154294 | 0.77 | MAOA (0.62) | HDAC1HDAC2MAOAMAOB | |
| SCHEMBL10722518 | 0.77 | HDAC1 (0.57) | HDAC1HDAC2MAOAMAOBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080199933-A1 | Amine Oxidase Inhibitors | SAYRE LAWRENCE M | 2008-08-21 | — | — | US | disclosed |
| EP-0330218-B1 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMA (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5252608-A | Preventing the abnormal deposition of collagen by administering a halogenated allyl amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5182297-A | Thienylhaloallylamines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-26 | — | — | US | disclosed |
| US-5021456-A | Administering to treat dieseases of abnormal deposition of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4965288-A | ABNORMAL COLLAGEN DEPOSITION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-10-23 | — | — | US | disclosed |
| US-4943593-A | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-24 | — | — | US | disclosed |
| CN-1035497-A | The inhibitor of lysyloxidase | MERRELL DOW PHARMA (US) | 1989-09-13 | — | — | CN | disclosed |
| EP-0330218-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | disclosed |
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | disclosed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | disclosed |