Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154435 | 0.91 | MAPT (0.44) | ALDH1A1GAAALOX15MAPTSMN1; SMN2 | |
| SCHEMBL9158333 | 0.90 | GAA (0.46) | ALDH1A1GAAALOX15MAPTKMT2A | |
| SCHEMBL9159956 | 0.87 | PPIB (0.43) | ALDH1A1GAAALOX15MAPTSMN1; SMN2 | |
| SCHEMBL9158010 | 0.86 | PPIB (0.44) | ALDH1A1GAAALOX15MAPTSMN1; SMN2 | |
| SCHEMBL9153919 | 0.85 | MAPT (0.40) | ALDH1A1GAAALOX15MAPTPPID | |
| SCHEMBL9155935 | 0.85 | PPIB (0.44) | ALDH1A1GAAALOX15MAPTSMN1; SMN2 | |
| SCHEMBL9158391 | 0.84 | HPSE (0.46) | ALDH1A1GAAALOX15MAPTKMT2A | |
| SCHEMBL29422582 | 0.84 | HPSE (0.46) | ALDH1A1GAAALOX15MAPTKMT2A | |
| SCHEMBL9134555 | 0.84 | KMT2A (0.44) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9159354 | 0.83 | MAPT (0.52) | ALDH1A1MAPTSMN1; SMN2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |