Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | GALR3 | O60755 | 1/20 | 0.65 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.65 |
| ▸ | GPR183 | P32249 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154602 | 1.00 | MEN1 (0.65) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9156982 | 0.89 | NPC1 (0.70) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9511583 | 0.85 | MEN1 (0.73) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9156624 | 0.85 | RAB9A (0.64) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9156024 | 0.85 | RAB9A (0.64) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9096458 | 0.83 | MEN1 (0.73) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9240100 | 0.82 | NPC1 (0.82) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9775193 | 0.81 | NPC1 (0.81) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9507031 | 0.81 | MEN1 (0.70) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9236624 | 0.81 | MEN1 (0.70) | MEN1NPC1GALR3NR2F2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391390-B1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINI RICERCA SCIENT TECNOLOG (IT) | 1995-02-08 | — | — | EP | claimed |
| US-5169848-A | Insecticides, miticides | PRESIDENZA DEL CONSIGLIO DEI MINISTRI-UFFICIO DEL MINISTRO PER IL COORDINAMENTO DELLE INIZIATIVE PER LA RICERVA SCIENTIFICA E TECNOLOGICA (IT) | 1992-12-08 | — | — | US | claimed |
| EP-0391390-A1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-10-10 | — | — | EP | claimed |
| EP-0391390-B1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINI RICERCA SCIENT TECNOLOG (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5169848-A | Insecticides, miticides | PRESIDENZA DEL CONSIGLIO DEI MINISTRI-UFFICIO DEL MINISTRO PER IL COORDINAMENTO DELLE INIZIATIVE PER LA RICERVA SCIENTIFICA E TECNOLOGICA (IT) | 1992-12-08 | — | — | US | disclosed |
| EP-0391390-A1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-10-10 | — | — | EP | disclosed |