Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.38 |
| ▸ | DRD3 | P35462 | 7/20 | 0.36 |
| ▸ | DRD4 | P21917 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804458 | 1.00 | DRD2 (0.38) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL8649163 | 0.94 | DRD2 (0.34) | DRD2DRD3DRD4HTR1ACA12 | |
| Isothiocyanate SCHEMBL11011138 | 0.90 | DRD2 (0.34) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL7372904 | 0.85 | DRD2 (0.36) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL8799867 | 0.82 | CHRNB2 (0.37) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL8436147 | 0.80 | POLB (0.42) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL11445454 | 0.80 | DRD2 (0.36) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL11300057 | 0.80 | POLB (0.42) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL11251940 | 0.80 | DRD2 (0.36) | DRD2DRD3DRD4HTR1ACA12 | |
| SCHEMBL9036814 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1298702-C | Process for preparing (s)-1-allyl-2-amidomethyl tetrahydropyrrole | JIANGSU PROV ATOM MEDICINE INS (CN) | 2007-02-07 | — | — | CN | disclosed |
| CN-1298702-C | Process for preparing (s)-1-allyl-2-amidomethyl tetrahydropyrrole | JIANGSU PROV ATOM MEDICINE INS (CN) | 2007-02-07 | — | — | CN | disclosed |
| CN-1683335-A | Process for preparing (S)-1-allyl-2-amidomethyl tetrahydropyrrole | JIANGSU PROV ATOM MEDICINE INS (CN) | 2005-10-19 | — | — | CN | disclosed |
| CN-1683335-A | Process for preparing (S)-1-allyl-2-amidomethyl tetrahydropyrrole | JIANGSU PROV ATOM MEDICINE INS (CN) | 2005-10-19 | — | — | CN | disclosed |
| US-5468876-A | Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines | AKTIEBOLAGET ASTRA (SE) | 1995-11-21 | — | — | US | disclosed |
| US-5300660-A | Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1994-04-05 | — | — | US | disclosed |
| EP-0253785-B1 | EFFICIENT STEREOCONSERVATIVE SYNTHESES OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THEREIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0270596-A1 | A STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THERETO | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-06-15 | — | — | EP | disclosed |
| WO-1987007271-A1 | A STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THERETO | Astra Läkemedel Aktiebolag (SE) | 1987-12-03 | — | — | WO | disclosed |