Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161283 | 0.92 | ALOX5 (0.45) | ALOX5DYRK1ACA12CA9NPC1 | |
| SCHEMBL9153216 | 0.91 | ALOX5 (0.52) | ALOX5DYRK1A | |
| SCHEMBL9155047 | 0.91 | ALOX5 (0.52) | ALOX5DYRK1ACA12CA9 | |
| SCHEMBL9161507 | 0.87 | ALOX5 (0.42) | ALOX5DYRK1ACA12CA9NPC1 | |
| SCHEMBL9158135 | 0.83 | ALOX5 (0.42) | ALOX5DYRK1ACA12CA9NPC1 | |
| SCHEMBL9156957 | 0.83 | MAOB (0.39) | ALOX5MAOB | |
| SCHEMBL9261102 | 0.82 | MAOB (0.49) | ALOX5NPC1ALDH1A1HPGDMAOB | |
| SCHEMBL9159702 | 0.80 | GRM4 (0.40) | ALOX5 | |
| SCHEMBL9301706 | 0.79 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9156981 | 0.79 | F10 (0.41) | ALOX5NPC1ALDH1A1HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410054-A | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1995-04-25 | — | — | US | disclosed |