Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 18/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161437 | 0.90 | GRM4 (0.39) | GRM4ALOX5TLR8 | |
| SCHEMBL9161176 | 0.87 | GRM4 (0.39) | GRM4ALOX5TLR8 | |
| SCHEMBL9261102 | 0.83 | MAOB (0.49) | ALOX5 | |
| SCHEMBL9302861 | 0.81 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9301706 | 0.81 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9301699 | 0.80 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9154909 | 0.80 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9301510 | 0.80 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9301723 | 0.78 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9154676 | 0.77 | GRM4 (0.38) | GRM4ALOX5TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410054-A | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1995-04-25 | — | — | US | disclosed |