SCHEMBL9155147

SCHEMBL9155147

Cc1ccc(S(=O)(=O)Oc2ccc(C=O)cc2OS(=O)(=O)c2ccc(C)c(O)c2)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.52
HPGD P15428 5/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 1/20 0.52
GAA P10253 3/20 0.49
GFER P55789 1/20 0.46
AOX1 Q06278 1/20 0.44
TRIM24 O15164 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197684 0.86 ALDH1A1 (0.50) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL9160418 0.83 ALDH1A1 (0.54) ALDH1A1HPGDSMN1; SMN2MAPK1TDP1
SCHEMBL9155140 0.81 GFER (0.61) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL9157040 0.80 ALDH1A1 (0.45) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
Isovanillin SCHEMBL1936859 0.77 HPGD (0.63) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL1936658 0.75 GFER (0.72) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL1935202 0.75 HPGD (0.67) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL15631695 0.74 GFER (0.53) ALDH1A1HPGDSMN1; SMN2MAPK1GAA
SCHEMBL29956905 0.74 KDM4E (0.64) ALDH1A1HPGDAOX1TRIM24ALDH5A1
SCHEMBL111227 0.74 KDM4E (0.64) ALDH1A1HPGDAOX1TRIM24ALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510445-B1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AG (DE) 1995-08-09 EP disclosed
EP-0510444-B1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AG (DE) 1995-02-01 EP disclosed
EP-0510444-A1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
EP-0510445-A1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed