SCHEMBL9197684

SCHEMBL9197684

Cc1ccc(S(=O)(=O)Oc2cc(C=O)cc(OS(=O)(=O)c3ccc(C)c(O)c3)c2OS(=O)(=O)c2ccc(C)c(O)c2)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.50
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 1/20 0.41
GAA P10253 4/20 0.39
GFER P55789 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
MAPT P10636 1/20 0.38
TRIM24 O15164 1/20 0.38
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALPL P05186 4/20 0.36
ALPI P09923 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155147 0.86 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDMAPK1GAA
SCHEMBL9197679 0.81 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2HPGDMAPK1GAA
SCHEMBL9160418 0.81 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HPGDMAPK1MEN1
SCHEMBL9157040 0.77 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2HPGDMAPK1GAA
SCHEMBL8837665 0.74 MEN1 (0.53) SMN1; SMN2MAPK1GAAMEN1KMT2A
SCHEMBL12119951 0.73 GFER (0.52) ALDH1A1SMN1; SMN2HPGDMAPK1GAA
SCHEMBL8837717 0.72 ESR1 (0.48) GAAMEN1KMT2AESR1ESR2
SCHEMBL8837597 0.72 TUBB4A (0.48) GAAMEN1KMT2AESR1ESR2
SCHEMBL21993216 0.70 GFER (0.58) ALDH1A1SMN1; SMN2HPGDMAPK1GAA
SCHEMBL31013906 0.69 GFER (0.50) ALDH1A1SMN1; SMN2HPGDMAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510445-B1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AG (DE) 1995-08-09 EP disclosed
EP-0510445-A1 Acid-cleavable radiation-sensitive compounds, radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed