Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19702985 | 1.00 | TSHR (0.46) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL7932707 | 0.98 | TSHR (0.42) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL26193033 | 0.91 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL1398289 | 0.91 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL18031715 | 0.91 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL26193035 | 0.91 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL23499896 | 0.89 | TSHR (0.39) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL387078 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL6064484 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL6064240 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAMAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424959-B1 | Organosilylalkyl-aromatic compounds | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0424959-A2 | Organosilylalkyl-aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1991-05-02 | — | — | EP | disclosed |