Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155232 | 0.98 | TSHR (0.46) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL19702985 | 0.98 | TSHR (0.46) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL23499896 | 0.91 | TSHR (0.39) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL18031715 | 0.89 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1398289 | 0.89 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL296166 | 0.84 | ALDH1A1 (0.44) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL12972072 | 0.84 | TSHR (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL17123369 | 0.82 | ALDH1A1 (0.33) | TSHRALDH1A1LMNA | |
| SCHEMBL6064484 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL6064240 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1LMNALPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491206-A | MOLDING MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-13 | — | — | US | claimed |
| US-12479867-B2 | Processes for synthesizing unsymmetrical disiloxanes | DOW SILICONES CORPORATION (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250122229-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBINOL FUNCTIONALITY | DOW SILICONES CORP (US) | 2025-04-17 | — | — | US | disclosed |
| EP-4508054-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH VINYLESTER FUNCTIONALITY | Dow Global Technologies LLC (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250051524-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBOXY FUNCTIONALITY | DOW SILICONES CORP (US) | 2025-02-13 | — | — | US | disclosed |
| EP-4496833-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBOXY FUNCTIONALITY | Dow Global Technologies LLC (US) | 2025-01-29 | — | — | EP | disclosed |
| US-12180238-B2 | Process for synthesizing alkenyl disiloxane | DOW SILICONES CORPORATION (US) | 2024-12-31 | — | — | US | disclosed |
| EP-4437031-A2 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBINOL FUNCTIONALITY | Dow Global Technologies LLC (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023201146-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH VINYLESTER FUNCTIONALITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023183682-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBOXY FUNCTIONALITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-1993013171-A2 | POLYMERIZABLE COMPOSITIONS CONTAINING OLEFIN METATHESIS CATALYSTS AND COCATALYSTS, AND METHODS OF USE THEREFOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0546716-A1 | Hydrosilylation process | Dow Corning Limited (GB) | 1993-06-16 | — | — | EP | disclosed |
| EP-0535687-A1 | Preparation process of silicone resin | WACKER-CHEMIE GMBH (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-5198511-A | Polymerizable compositions containing olefin metathesis catalysts and cocatalysts, and methods of use therefor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| EP-0446030-A2 | Solventless silicone release coating | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0217334-B1 | RADIATION-CURABLE ORGANOPOLYSILOXANE COATING COMPOSITION | DOW CORNING CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4980439-A | Method for manufacturing an alkenyl group-containing organopolysiloxane | TORAY SILICONE COMPANY LIMITED (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0361477-A2 | Method for manufacturing an alkenyl group-containing organopolysiloxane | TORAY SILICONE COMPANY, LIMITED (JP) | 1990-04-04 | — | — | EP | disclosed |
| EP-0217334-A2 | Radiation-curable organopolysiloxane coating composition | DOW CORNING CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4596720-A | Radiation-curable organopolysiloxane coating composition | DOW CORNING CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122229-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBINOL FUNCTIONALITY | SI, HPD, ACMSD | TSHR 4695/4885ALDH1A1 226/4885LMNA 3759/4885 |
| US-20250051524-A1 | PREPARATION OF ORGANOSILICON COMPOUNDS WITH CARBOXY FUNCTIONALITY | AOX1, CBR1, CBR3 | TSHR 4873/4885ALDH1A1 81/4885LMNA 3794/4885 |
| US-12180238-B2 | Process for synthesizing alkenyl disiloxane | FHIT, SLC9B2, SLC6A9 | TSHR 3096/4885ALDH1A1 1029/4885LMNA 935/4885 |
| US-12479867-B2 | Processes for synthesizing unsymmetrical disiloxanes | DEGS1, CNOT7, HACL2 | TSHR 4258/4885ALDH1A1 3220/4885LMNA 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.