Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151412 | 0.85 | CHRM2 (0.39) | CHRM2CHRM1 | |
| SCHEMBL9147996 | 0.80 | CHRM2 (0.51) | CHRM2CHRM1 | |
| SCHEMBL9155101 | 0.77 | CHRM2 (0.41) | CHRM2CHRM1 | |
| SCHEMBL9147958 | 0.77 | CHRM2 (0.41) | CHRM2CHRM1 | |
| SCHEMBL9147955 | 0.77 | CHRM2 (0.41) | CHRM2CHRM1 | |
| SCHEMBL9149463 | 0.76 | CHRM2 (0.40) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9148283 | 0.75 | CHRM2 (0.40) | CHRM2CHRM1 | |
| SCHEMBL9150745 | 0.72 | CHRM2 (0.42) | CHRM2 | |
| SCHEMBL9151188 | 0.71 | CHRNA7 (0.43) | CHRM2CHRM1 | |
| Oxalic Acid SCHEMBL9152500 | 0.70 | CHRM2 (0.36) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | claimed |
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0307142-B1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-09-14 | — | — | EP | disclosed |