SCHEMBL9155338

SCHEMBL9155338

COc1cccc(Oc2cc(O)c3c(c2N)C(=O)c2ccccc2C3=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.48
ADORA1 P30542 1/20 0.46
P2RY4 P51582 3/20 0.46
P2RY2 P41231 2/20 0.46
P2RY12 Q9H244 2/20 0.46
MAPT P10636 6/20 0.46
TSHR P16473 2/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
RECQL P46063 2/20 0.44
THRB P10828 2/20 0.44
ESR2 Q92731 1/20 0.44
EGFR P00533 1/20 0.44
PIM1 P11309 1/20 0.44
PGAM1 P18669 1/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731564 0.90 ADORA2A (0.50) ADORA2AP2RY4P2RY2MAPTTSHR
SCHEMBL31037853 0.90 ADORA2A (0.50) ADORA2AP2RY4P2RY2MAPTTSHR
SCHEMBL92408 0.88 ALDH1A1 (0.49) ADORA2AP2RY4P2RY2P2RY12MAPT
SCHEMBL8748152 0.87 MAPT (0.50) ADORA2AADORA1P2RY4P2RY2P2RY12
SCHEMBL10809923 0.87 ADORA2A (0.50) ADORA2AP2RY2P2RY12MAPTPOLB
SCHEMBL11119162 0.87 ADORA2A (0.50) ADORA2AP2RY4P2RY2P2RY12MAPT
SCHEMBL92475 0.87 ADORA2A (0.62) ADORA2AP2RY4P2RY2P2RY12MAPT
SCHEMBL27919412 0.85 ADORA2A (0.48) ADORA2AP2RY4P2RY2P2RY12MAPT
SCHEMBL11525041 0.84 KMT2A (0.42) ADORA2AMAPTTSHRPOLBSMN1; SMN2
SCHEMBL9160516 0.84 ADORA2A (0.45) ADORA2AP2RY2P2RY12MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330487-B1 Color toner composition MITSUI TOATSU CHEMICALS (JP) 1995-01-25 EP disclosed
US-4954410-A Amino and phenoxy or thiophenoxy substituted anthraquinone dyes MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-09-04 US disclosed
EP-0330487-A2 Color toner composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed