SCHEMBL8748152

SCHEMBL8748152

COc1cccc(Oc2cc(N)c3c(c2N)C(=O)c2ccccc2C3=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
ADORA2A P29274 4/20 0.50
ALDH1A1 P00352 4/20 0.50
POLB P06746 4/20 0.50
NPSR1 Q6W5P4 3/20 0.50
MAPK1 P28482 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
THRB P10828 2/20 0.50
FGB P02675 1/20 0.50
PPARG P37231 1/20 0.50
RAB9A P51151 1/20 0.50
NCOA2 Q15596 1/20 0.50
NCOA1 Q15788 1/20 0.50
ADORA1 P30542 1/20 0.48
P2RY4 P51582 5/20 0.47
P2RY2 P41231 4/20 0.47
P2RY12 Q9H244 2/20 0.47
KDM4E B2RXH2 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155338 0.87 ADORA2A (0.48) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL92465 0.87 ALDH1A1 (0.55) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL10808924 0.86 ADORA2A (0.52) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL92415 0.86 ADORA2A (0.66) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL8748104 0.84 ADORA2A (0.50) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL8748263 0.84 ADORA2A (0.50) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL9151959 0.83 ADORA2A (0.52) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL460432 0.83 MAPT (0.66) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL11759211 0.82 ADORA2A (0.45) MAPTMEN1KMT2AADORA2AALDH1A1
SCHEMBL10906307 0.81 ADORA2A (0.52) MAPTMEN1KMT2AADORA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323744-B1 Transfer sheet ink and method for sublimation thermal-transfer printing MITSUI TOATSU CHEMICALS (JP) 1997-03-19 EP disclosed
US-5300475-A Anthraquinone dyes MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-04-05 US disclosed
US-5168093-A Colorfast anthraquinone dyes MITSUI TOATSU CHEMICALS INC. (JP) 1992-12-01 US disclosed
EP-0323744-A2 Transfer sheet ink and method for sublimation thermal-transfer printing MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-07-12 EP disclosed