Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29912717 | 1.00 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL34472768 | 0.88 | NR4A1 (0.38) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL11387114 | 0.84 | NR4A1 (0.53) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL3395153 | 0.82 | ALDH1A1 (0.42) | NR4A1NR4A2NR4A3HDAC8ALDH1A1 | |
| SCHEMBL9620093 | 0.80 | L3MBTL1 (0.50) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL15385197 | 0.79 | NR4A1 (0.61) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| Alcohol SCHEMBL28412139 | 0.77 | NR4A1 (0.46) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL6379741 | 0.77 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL30719419 | 0.77 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL7803256 | 0.77 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MMP3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386057-A | Process for the preparation of acyl isocyanates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1995-01-31 | — | — | US | disclosed |