Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150938 | 0.87 | KDM4E (0.48) | CAMK2AKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL8002569 | 0.87 | MTNR1B (0.54) | KDM4EALDH1A1P2RX4MEN1TSHR | |
| SCHEMBL9151951 | 0.86 | MTNR1B (0.53) | KDM4EALDH1A1P2RX4MEN1TSHR | |
| SCHEMBL837233 | 0.85 | RIPK1 (0.51) | CAMK2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL9152712 | 0.85 | MAOB (0.45) | CYP3A4KDM4EALDH1A1P2RX4MEN1 | |
| SCHEMBL9420375 | 0.84 | CAMK2A (0.68) | CAMK2ACYP3A4THRATHRBCXCL8 | |
| SCHEMBL9151211 | 0.84 | MEN1 (0.45) | TTRKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL9147925 | 0.83 | HSP90AB1 (0.44) | CAMK2ATTRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9152628 | 0.83 | GAA (0.46) | MEN1KMT2AMTNR1BSLC1A5GAA | |
| SCHEMBL9152338 | 0.83 | MEN1 (0.47) | KDM4EALDH1A1MEN1KMT2AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468857-A | Phenylmethoxypropenoic esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-21 | — | — | US | disclosed |
| EP-0307103-B1 | Fungicides | ZENECA LTD (GB) | 1994-09-21 | — | — | EP | disclosed |
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| EP-0307103-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |