Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153224 | 0.91 | HSD17B10 (0.47) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9158123 | 0.89 | HSD17B10 (0.49) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11183963 | 0.83 | FABP4 (0.64) | HSD17B10ALDH1A1KDM4EFABP4FABP5 | |
| SCHEMBL11185535 | 0.81 | FABP4 (0.63) | HSD17B10KDM4EFABP4FABP5 | |
| SCHEMBL11191303 | 0.80 | KDM4E (0.68) | HSD17B10ALDH1A1KDM4EMAPTFABP4 | |
| SCHEMBL9158043 | 0.79 | MEN1 (0.64) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27973386 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11189549 | 0.79 | HSD17B10 (0.56) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11192095 | 0.77 | KDM4E (0.67) | HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11184588 | 0.76 | TNF (0.58) | HSD17B10ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |