Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381468 | 0.86 | ALDH1A1 (0.71) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28973475 | 0.83 | KDM4E (0.68) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL388824 | 0.82 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4096894 | 0.82 | KDM4E (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9158123 | 0.81 | HSD17B10 (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12301950 | 0.80 | MEN1 (0.75) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9155545 | 0.79 | HSD17B10 (0.57) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30367071 | 0.79 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17066941 | 0.79 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5435816 | 0.79 | KDM4E (0.63) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |