Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102488 | 0.89 | BTK (0.42) | MAPTL3MBTL1PGRRORARORC | |
| SCHEMBL9153178 | 0.83 | KMO (0.39) | MAPTBRPF1KMONAMPTSCN7A | |
| SCHEMBL17979387 | 0.83 | MAPT (0.45) | MAPTRXFP1L3MBTL1PGRRORA | |
| SCHEMBL9310207 | 0.79 | BTK (0.52) | MAPTRXFP1KDM4EPOLBBTK | |
| SCHEMBL4101677 | 0.78 | CA12 (0.50) | BRPF1NAMPTCA12CA9MEN1 | |
| SCHEMBL2796642 | 0.75 | MAPT (0.40) | MAPTRXFP1L3MBTL1KDM4EPOLB | |
| SCHEMBL14564431 | 0.74 | KDM4E (0.49) | MAPTL3MBTL1KDM4EPOLBHSD17B10 | |
| SCHEMBL422084 | 0.73 | BRPF1 (0.65) | MAPTRXFP1BRPF1THRBCA12 | |
| SCHEMBL1037171 | 0.73 | CA12 (0.49) | BRPF1NAMPTCA12CA9KMT2A | |
| SCHEMBL1034534 | 0.72 | CA12 (0.47) | BRPF1NAMPTCA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |