Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155610 | 1.00 | ITGB3 (0.42) | ITGB3ITGA2BBCHERARBMEN1 | |
| SCHEMBL9152197 | 0.99 | ITGB3 (0.40) | ITGB3ITGA2BBCHERARBMEN1 | |
| SCHEMBL9152195 | 0.99 | ITGB3 (0.40) | ITGB3ITGA2BBCHERARBMEN1 | |
| SCHEMBL9155936 | 0.95 | HRH1 (0.38) | ITGB3ITGA2BBCHEALDH1A1KMT2A | |
| SCHEMBL9155939 | 0.95 | HRH1 (0.38) | ITGB3ITGA2BBCHEALDH1A1KMT2A | |
| SCHEMBL9489400 | 0.91 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489407 | 0.91 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489367 | 0.91 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489031 | 0.91 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9488833 | 0.90 | RARB (0.47) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411676-A | Ferroelectric electrooptical indicators | HOFFMANN-LA ROCHE INC. (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0415220-B1 | Chiral doping agents for liquid crystals | HOFFMANN LA ROCHE (CH) | 1994-02-02 | — | — | EP | disclosed |
| US-5093027-A | CHIRAL DOPANTS FOR LIQUID CRYSTALLINE MIXTURES | HOFFMANN-LA ROCHE INC. (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0415220-A2 | Chiral doping agents for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-06 | — | — | EP | disclosed |