Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 9/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 7/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489031 | 1.00 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489407 | 1.00 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489400 | 1.00 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9488833 | 0.99 | RARB (0.47) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489091 | 0.95 | TRPV1 (0.47) | RARBALDH1A1KMT2ATHRATHRB | |
| SCHEMBL9488730 | 0.94 | MAPT (0.45) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9489140 | 0.92 | MAPT (0.46) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9155610 | 0.91 | ITGB3 (0.42) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9155603 | 0.91 | ITGB3 (0.42) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9490214 | 0.90 | ALDH1A1 (0.44) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | claimed |
| US-5236618-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4744918-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-05-17 | — | — | US | disclosed |
| EP-0168043-A2 | Liquid crystal phase | MERCK PATENT GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |