Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151594 | 0.92 | MAPT (0.40) | MAPTALDH1A1HPGDHTTANPEP | |
| SCHEMBL9151422 | 0.88 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDANPEPRXRA | |
| SCHEMBL9153576 | 0.84 | TP53 (0.46) | MAPTALDH1A1TP53TSHRKMT2A | |
| SCHEMBL9153474 | 0.83 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDHTTANPEP | |
| SCHEMBL9157993 | 0.83 | TP53 (0.48) | MAPTALDH1A1TP53TSHRKMT2A | |
| SCHEMBL9156260 | 0.80 | KMT2A (0.44) | MAPTALDH1A1HPGDANPEPRXRA | |
| SCHEMBL9448556 | 0.80 | ANPEP (0.46) | MAPTALDH1A1HPGDHTTANPEP | |
| SCHEMBL3789520 | 0.79 | MAPT (0.44) | MAPTALDH1A1HPGDHTTANPEP | |
| SCHEMBL9151113 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDHTTANPEPRXRA | |
| SCHEMBL938192 | 0.73 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDHTTANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424959-B1 | Organosilylalkyl-aromatic compounds | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5210247-A | ORGANOSILYLALKYLAROMATIC COMPOUNDS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0424959-A2 | Organosilylalkyl-aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1991-05-02 | — | — | EP | disclosed |