Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442501 | 0.84 | CYP17A1 (0.34) | MAPT | |
| SCHEMBL9153474 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1CA1CA2HTT | |
| SCHEMBL17888500 | 0.79 | ESR1 (0.50) | MAPTTSHR | |
| SCHEMBL9155644 | 0.79 | MAPT (0.43) | MAPTALDH1A1CA1CA2HTT | |
| SCHEMBL2822248 | 0.78 | LMNA (0.43) | HTTTSHRKMT2A | |
| SCHEMBL9448556 | 0.78 | ANPEP (0.46) | MAPTALDH1A1HTTANPEPRXRA | |
| SCHEMBL5361409 | 0.77 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5048126 | 0.75 | FAAH (0.32) | ALDH1A1TSHR | |
| SCHEMBL9151594 | 0.75 | MAPT (0.40) | MAPTALDH1A1CA1CA2HTT | |
| SCHEMBL938192 | 0.74 | ALDH1A1 (0.56) | MAPTALDH1A1CA1CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420049-B1 | SURFACE-TREATED INORGANIC PARTICLES | KANEKA CORP (JP) | 2010-04-21 | — | — | EP | disclosed |
| US-20040197561-A1 | Process for producing surface-treated inorganic particle and surface-treated inogranic particle | KANEKA CORPORATION (JP) | 2004-10-07 | — | — | US | disclosed |
| EP-1420049-A1 | PROCESS FOR PRODUCING SURFACE−TREATED INORGANIC PARTICLE AND SURFACE−TREATED INORGANIC PARTICLE | KANEKA CORPORATION (JP) | 2004-05-19 | — | — | EP | disclosed |