Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | NSD2 | O96028 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
| ▸ | SNCA | P37840 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074561 | 0.86 | ALDH1A1 (0.76) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL13476258 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL17167123 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL23351420 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL24074836 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL19846480 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL9155731 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL13085757 | 0.74 | MAPT (0.58) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL24073136 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL24074587 | 0.71 | KDM4E (0.75) | KDM4EALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406812-B1 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INC (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5097029-A | Hydrolysis, alkylation, intermediates for azo dyes | HERCULES INCORPORATED (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |