Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155943 | 1.00 | KMT2A (0.37) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9158122 | 0.96 | KMT2A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9158129 | 0.96 | KMT2A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9158127 | 0.96 | KMT2A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9158143 | 0.96 | KMT2A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9157988 | 0.96 | MEN1 (0.36) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9157975 | 0.96 | MEN1 (0.36) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9766615 | 0.95 | RAB9A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9766610 | 0.95 | RAB9A (0.35) | KMT2AMAPTCYP1A2MEN1L3MBTL1 | |
| SCHEMBL9156179 | 0.92 | MEN1 (0.34) | KMT2AMAPTCYP1A2MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |