Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766610 | 1.00 | RAB9A (0.35) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9157975 | 0.96 | MEN1 (0.36) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9157988 | 0.96 | MEN1 (0.36) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9155943 | 0.95 | KMT2A (0.37) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9155950 | 0.95 | KMT2A (0.37) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9156179 | 0.92 | MEN1 (0.34) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9156198 | 0.92 | MEN1 (0.34) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9156186 | 0.92 | MEN1 (0.34) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9156191 | 0.92 | MEN1 (0.34) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 | |
| SCHEMBL9591840 | 0.92 | MAOB (0.38) | RAB9ANPC1SMN1; SMN2NFKB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |