Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156264 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL29131651 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL6623670 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL11594134 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL4294754 | 0.78 | KMT2A (0.54) | GAAKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL9154000 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNATP53GAAKMT2A | |
| SCHEMBL9153991 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNATP53GAAKMT2A | |
| SCHEMBL8074258 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL10594096 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNATP53SMN1; SMN2GAA | |
| SCHEMBL1822378 | 0.75 | KMT2A (0.44) | LMNASMN1; SMN2KMT2ACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |