Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921004 | 0.91 | SMYD2 (0.42) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL17755998 | 0.89 | SMYD2 (0.42) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL1291772 | 0.89 | LMNA (0.42) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL29102862 | 0.86 | SMYD2 (0.38) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL31049119 | 0.85 | SMYD2 (0.40) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL26264744 | 0.84 | SMYD2 (0.38) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL1291773 | 0.84 | LMNA (0.40) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL3078638 | 0.84 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2CYP3A4HTTPOLB | |
| SCHEMBL14117299 | 0.84 | SMYD2 (0.39) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL7336991 | 0.83 | SMYD2 (0.38) | SMYD2ALDH1A1SMN1; SMN2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189866-A1 | POLYMYXIN ANALOGS USEFUL AS ANTIBIOTIC POTENTIATORS | SPERO OPCO (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-0415198-B1 | Ketophosphamidyl glycosides, process for their preparation and their use as pharmaceutical agents | TIETZE LUTZ F PROF DR (DE) | 1995-01-25 | — | — | EP | disclosed |
| EP-0553673-A1 | N,N-bis-(2-chloroethyl)phosphoric acid diamidates as cytostatics | Tietze, Lutz F., Prof. Dr. (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-5132416-A | KETOPHOSPHAMIDE GLYCOSIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0415198-A2 | Ketophosphamidyl glycosides, process for their preparation and their use as pharmaceutical agents | Tietze, Lutz F., Prof. Dr. (DE) | 1991-03-06 | — | — | EP | disclosed |