Styrene

Styrene

SCHEMBL9156595

BrC=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
TSHR P16473 1/20 0.70
MAOB P27338 3/20 0.48
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 2/20 0.41
MAPK1 P28482 2/20 0.41
NFE2L2 Q16236 2/20 0.41
CYP19A1 P11511 2/20 0.41
MAOA P21397 2/20 0.41
TRPA1 O75762 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPT P10636 2/20 0.39
RECQL P46063 2/20 0.39
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6212318 0.89 ALDH1A1 (0.56) ALDH1A1TSHRMAOBTDP1LMNA
SCHEMBL6212311 0.89 ALDH1A1 (0.56) ALDH1A1TSHRMAOBTDP1LMNA
Butadiene SCHEMBL9067971 0.87 ALDH1A1 (0.50) ALDH1A1TSHRMAOBLMNAMAPK1
SCHEMBL1641281 0.87
SCHEMBL13704159 0.87
SCHEMBL331174 0.87
SCHEMBL25233314 0.86 ALDH1A1 (0.50) ALDH1A1TSHRMAOBTP53TDP1
SCHEMBL368442 0.84 ALDH1A1 (0.78) ALDH1A1TSHRMAOBNFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL28371714 0.84 ALDH1A1 (0.78) ALDH1A1TSHRMAOBNFE2L2CYP19A1
SCHEMBL16499669 0.84 ALDH1A1 (0.78) ALDH1A1TSHRMAOBNFE2L2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5426149-A Blend of epoxy modified styrene-styrene copolymer, conjugated diene-styrene copolymer with glass fiber reinforcement PHILLIPS PETROLEUM COMPANY (US) 1995-06-20 US disclosed
EP-0368237-B1 Polymer bound flame retardants ATOCHEM NORTH AMERICA (US) 1995-04-12 EP disclosed
US-5220015-A Having hydrazide group to chemically bond to anhydride-containing polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-06-15 US disclosed
US-5140070-A Halogenated aromatic compounds having acylamino functional groups bonded to imide containing polymer ELF ATOCHEM NORTH AMERICA, INC (US) 1992-08-18 US disclosed
EP-0195815-B1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5069818-A CHEMICAL RESISTANCE, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1991-12-03 US disclosed
US-5037894-A Maleic anhydride polymer reacted with halogenated hydrazide compound or derivative ATOCHEM NORTH AMERICA, INC. (US) 1991-08-06 US disclosed
EP-0436136-A1 Compatibilized polyphenylene ehter resin/nylon resin blends containing aromatic phosphorous-containing compounds GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP disclosed
EP-0368237-A2 Polymer bound flame retardants ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-05-16 EP disclosed
US-4824915-A COMPOUND CONTAINING ACYL HALIDE AND CARBOXYLIC ACID, ESTER, AMINE OR IMIDE GROUPS GENERAL ELECTRIC COMPANY (US) 1989-04-25 US disclosed
US-4164493-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1979-08-14 US disclosed
US-4154719-A ALKENYL AROMATIC RESIN MODIFIED WITH A DIENE RUBBER GENERAL ELECTRIC COMPANY (US) 1979-05-15 US disclosed
US-4152316-A COMPOSITIONS OF A POLYPHENYLENE ETHER RESIN AND ALKENYL AROMATIC RESINS MODIFIED WITH EPDM RUBBER GENERAL ELECTRIC COMPANY (US) 1979-05-01 US disclosed
US-4143095-A MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1979-03-06 US disclosed
US-4139574-A Impact resistant polyphenylene ether resin compositions containing EPDM rubber-modified alkenyl aromatic resins and hydrogenated radial teleblock copolymers GENERAL ELECTRIC COMPANY (US) 1979-02-13 US disclosed
US-4127558-A Compositions of a polyphenylene ether resin and alkenyl aromatic resins modified with EPDM rubber containing propylene GENERAL ELECTRIC COMPANY (US) 1978-11-28 US disclosed
US-4102850-A MONO-OLEFIN-POLYENE MODIFIED ALKENYL AROMATIC RESIN GENERAL ELECTRIC COMPANY (US) 1978-07-25 US disclosed
US-4101503-A Compositions of a polyphenylene ether resin and high molecular weight alkenyl aromatic resins modified with EPDM rubber GENERAL ELECTRIC COMPANY (US) 1978-07-18 US disclosed
US-4101505-A Compositions of a polyphenylene ether resin and EPDM rubber-modified alkenyl aromatic resins having specified gel content GENERAL ELECTRIC COMPANY (US) 1978-07-18 US disclosed
US-4101504-A High impact compositions of a polyphenylene ether resin and alkenyl aromatic resins modified with EPDM rubber GENERAL ELECTRIC COMPANY (US) 1978-07-18 US disclosed