Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHAT | P28329 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368442 | 1.00 | ALDH1A1 (0.78) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL27498688 | 0.97 | ALDH1A1 (0.82) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28371714 | 0.94 | ALDH1A1 (0.78) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| SCHEMBL10381868 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| SCHEMBL10381869 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| Styrene SCHEMBL490169 | 0.91 | ALDH1A1 (0.93) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| Styrene SCHEMBL369036 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| Styrene SCHEMBL11144289 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| Styrene SCHEMBL6258482 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 | |
| Styrene SCHEMBL4986035 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRMAOBNFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840076-B1 | BICYCLIC COMPOUND | TOA EIYO LTD (JP) | 2017-10-25 | — | — | EP | disclosed |
| CN-104245663-B | Bicyclic compounds | 东亚荣养株式会社 | 2016-10-26 | — | — | CN | disclosed |
| US-9290440-B2 | Bicyclic compound | TOA EIYO LTD. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20150119418-A1 | BICYCLIC COMPOUND | TOA EIYO LTD. (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2840076-A1 | BICYCLIC COMPOUND | TOA Eiyo Ltd. (JP) | 2015-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119418-A1 | BICYCLIC COMPOUND | C1S, C1R, CYP11B2 | ALDH1A1 2350/4885TSHR 2380/4885MAOB 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.