SCHEMBL915665

SCHEMBL915665

O=C(O)C=Cc1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.67
HDAC4 P56524 3/20 0.67
HDAC1 Q13547 3/20 0.67
HDAC2 Q92769 3/20 0.67
HDAC8 Q9BY41 3/20 0.67
HDAC6 Q9UBN7 3/20 0.67
HCAR2 Q8TDS4 2/20 0.67
HDAC7 Q8WUI4 2/20 0.67
HDAC10 Q969S8 2/20 0.67
HDAC11 Q96DB2 2/20 0.67
HDAC9 Q9UKV0 2/20 0.67
HDAC5 Q9UQL6 2/20 0.67
TNKS O95271 1/20 0.67
TNKS2 Q9H2K2 1/20 0.67
FFAR1 O14842 2/20 0.58
ESR1 P03372 2/20 0.57
ESR2 Q92731 2/20 0.57
CA12 O43570 2/20 0.57
AKR1B10 O60218 2/20 0.57
CA1 P00915 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4246009 0.85 TRPA1 (0.48) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL10747786 0.81 HDAC1 (0.91) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL10747781 0.81 HDAC1 (0.91) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL10747790 0.81 HDAC1 (0.91) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL1332 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL1706935 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL50466 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL653828 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL3406486 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8
Cinnamic Acid SCHEMBL653827 0.81 HCAR2 (1.00) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8915374-B2 Flotation aids and processes for using the same THE UNIVERSITY OF MELBOURNE (AU) 2014-12-23 US claimed
US-8486274-B2 of solid suspensions within liquid medium; reversible stimulus to control inter-particle attraction or repulsion; consolidating a sediment bed; separating the resultant liquids-rich and solids-rich phases; stimulu is pH, temperature, wavelength of light, polyelectrolyte, chemical flocculant or dispersant NEWCASTLE INNOVATION LIMITED (AU) 2013-07-16 US claimed
US-20120160776-A1 STIMULANT SENSITIVE FLOCCULATION AND CONSOLIDATION THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 2012-06-28 US claimed
US-20110017676-A1 FLOTATION AIDS AND PROCESSES FOR USING THE SAME THE UNIVERSITY OF MELBOURNE (AU) 2011-01-27 US claimed
WO-2009089570-A1 FLOTATION AIDS AND PROCESSES FOR USING THE SAME THE UNIVERSITY OF MELBOURNE (AU) 2009-07-23 WO claimed
US-20080190860-A1 Stimulant Sensitive Flocculation and Consolidation UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 2008-08-14 US claimed
US-20220215216-A1 RECONSTRUCTED SEGMENTED CODES AND METHODS OF USING THE SAME RVC TECHNOLOGIES, INC. 2022-07-07 US disclosed
EP-3928226-A1 RECONSTRUCTED SEGMENTED CODES AND METHODS OF USING THE SAME RVC Technologies, Inc. (US) 2021-12-29 EP disclosed
US-9174860-B2 Stimulant sensitive flocculation and consolidation NEWCASTLE INNOVATION LIMITED (AU) 2015-11-03 US disclosed
US-8915374-B2 Flotation aids and processes for using the same THE UNIVERSITY OF MELBOURNE (AU) 2014-12-23 US disclosed
US-8486274-B2 of solid suspensions within liquid medium; reversible stimulus to control inter-particle attraction or repulsion; consolidating a sediment bed; separating the resultant liquids-rich and solids-rich phases; stimulu is pH, temperature, wavelength of light, polyelectrolyte, chemical flocculant or dispersant NEWCASTLE INNOVATION LIMITED (AU) 2013-07-16 US disclosed
US-20120160776-A1 STIMULANT SENSITIVE FLOCCULATION AND CONSOLIDATION THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 2012-06-28 US disclosed
US-20110017676-A1 FLOTATION AIDS AND PROCESSES FOR USING THE SAME THE UNIVERSITY OF MELBOURNE (AU) 2011-01-27 US disclosed
US-20110008427-A1 Microcapsules and Methods UNIVERSITY OF LEEDS (GB) 2011-01-13 US disclosed
WO-2009089570-A1 FLOTATION AIDS AND PROCESSES FOR USING THE SAME THE UNIVERSITY OF MELBOURNE (AU) 2009-07-23 WO disclosed
US-20080190860-A1 Stimulant Sensitive Flocculation and Consolidation UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) 2008-08-14 US disclosed