Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153388 | 0.89 | PYGM (0.36) | SMN1; SMN2MAPTNPC1RAB9APYGM | |
| SCHEMBL9153425 | 0.86 | HTT (0.48) | CA1CA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9154796 | 0.82 | NOTUM (0.39) | SMN1; SMN2MAPTALDH1A1PYGMPYGL | |
| SCHEMBL7400367 | 0.72 | CYP1A2 (0.52) | MAPTPYGMPYGLTSHRCYP1A2 | |
| SCHEMBL9154694 | 0.72 | PYGM (0.46) | SMN1; SMN2MAPTNPC1RAB9APYGM | |
| SCHEMBL12285143 | 0.71 | CA1 (0.59) | CA1CA2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL25837758 | 0.71 | CA1 (0.58) | CA1CA2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL114885 | 0.70 | CA1 (0.67) | CA1CA2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9153437 | 0.69 | HTT (0.46) | MAPTPYGMPYGLTSHRKDM4E | |
| SCHEMBL19553518 | 0.69 | CA1 (0.56) | CA1CA2SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403849-A | Treatment of central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | claimed |