Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 14/20 | 0.46 |
| ▸ | PYGL | P06737 | 13/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153388 | 0.80 | PYGM (0.36) | PYGMPYGLNPC1POLBRAB9A | |
| SCHEMBL9153437 | 0.79 | HTT (0.46) | PYGMPYGLMEN1CYP1A2CYP3A4 | |
| SCHEMBL29926641 | 0.78 | CYP1A2 (0.64) | PYGMPYGLMEN1CYP1A2CYP3A4 | |
| SCHEMBL7400360 | 0.78 | CYP1A2 (0.64) | PYGMPYGLMEN1CYP1A2CYP3A4 | |
| SCHEMBL7448031 | 0.78 | CYP1A2 (0.64) | PYGMPYGLMEN1CYP1A2CYP3A4 | |
| SCHEMBL9153403 | 0.76 | CTSA (0.37) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL6949414 | 0.75 | PYGM (0.49) | PYGMPYGLMEN1KMT2A | |
| SCHEMBL6953545 | 0.72 | PYGM (0.49) | PYGMPYGLMEN1KMT2A | |
| SCHEMBL6947702 | 0.72 | PYGM (0.53) | PYGMPYGLKMT2A | |
| SCHEMBL9156907 | 0.72 | CA1 (0.42) | PYGMPYGLNPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403849-A | Treatment of central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | claimed |