Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620457 | 0.86 | ALDH1A1 (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL7028923 | 0.85 | ALDH1A1 (0.70) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL18250877 | 0.83 | MAP4K4 (0.47) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL434861 | 0.80 | PDGFRB (0.59) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL444746 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL27918947 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL621672 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL27930034 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL1928147 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB | |
| SCHEMBL20033882 | 0.79 | PDGFRB (0.58) | ALDH1A1F2GLAHPGDPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442065-A | Antitumor agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-08-15 | — | — | US | disclosed |
| US-5442065-A | Antitumor agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-08-15 | — | — | US | disclosed |