Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811188 | 0.86 | HPGDS (0.60) | PDGFRBPDGFRAALDH1A1EGFRNCF1 | |
| SCHEMBL620427 | 0.86 | ALDH1A1 (0.54) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL7028923 | 0.85 | ALDH1A1 (0.70) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL434861 | 0.80 | PDGFRB (0.59) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL10556996 | 0.79 | PDGFRB (0.62) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL9156972 | 0.79 | ALDH1A1 (0.62) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL621672 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL27930034 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL444746 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1HPGDF2 | |
| SCHEMBL27918947 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1HPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119639239-A | Environment-friendly flame-retardant new energy charging pile cable | 瑞安达电缆有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-1930105-B | Process for preparing fluoroaromatic compounds from aminoaromatic amine compounds | RHONE POULENC CHIMIE | 2010-12-08 | — | — | CN | claimed |
| US-20070276168-A1 | Method For Preparation Of A Fluoroaromatic Compound From An Aminoaromatic Compound | RHODIA CHIMIE (FR) | 2007-11-29 | — | — | US | claimed |
| CN-1930105-A | Process for preparing fluoroaromatic compounds from aminoaromatic amine compounds | RHONE POULENC CHIMIE (FR) | 2007-03-14 | — | — | CN | claimed |
| EP-1713750-A1 | METHOD FOR PREPARATION OF A FLUOROARMATIC COMPOUND FROM AN AMINOAROMATIC AMINE COMPOUND | RHODIA CHIMIE (FR) | 2006-10-25 | — | — | EP | claimed |
| WO-2005082820-A1 | METHOD FOR PREPARATION OF A FLUOROAROMATIC COMPOUND FROM AN AMINOAROMATIC AMINE COMPOUND. | RHODIA CHIMIE (FR) | 2005-09-09 | — | — | WO | claimed |
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-119639239-A | Environment-friendly flame-retardant new energy charging pile cable | 瑞安达电缆有限公司 | 2025-03-18 | — | — | CN | disclosed |
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (US) | 2019-08-06 | — | — | US | disclosed |
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (US) | 2019-08-06 | — | — | US | disclosed |
| US-20190010126-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | Sanford Burnham Prebys Medical Discovery Institute | 2019-01-10 | — | — | US | disclosed |
| US-9884826-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884826-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2018-02-06 | — | — | US | disclosed |
| US-6603005-B2 | Bactericides | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | disclosed |
| WO-2003018021-A1 | 2,4-DISUBSTITUTED PYRIMIDINYL DERIVATIVES FOR USE AS ANTICANCER AGENTS | AMGEN INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20020177606-A1 | Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them | NOVEXEL (FR) | 2002-11-28 | — | — | US | disclosed |
| WO-2002072572-A1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2002-09-19 | — | — | WO | disclosed |
| US-20020111492-A1 | Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them | NOVEXEL (FR) | 2002-08-15 | — | — | US | disclosed |
| WO-2002040474-A2 | HETEROCYCLYLALKYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-05-23 | — | — | WO | disclosed |
| US-5442065-A | Antitumor agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | TNNI3, TNKS1BP1, TNNT2 | PDGFRB 3815/4885PDGFRA 2401/4885ALDH1A1 3674/4885 |
| US-20020111492-A1 | Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them | SYNJ1, NCAPD2, SYNJ2 | PDGFRB 3444/4885PDGFRA 2639/4885ALDH1A1 838/4885 |
| US-20190010126-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | TNNI3, TNKS1BP1, TNNT2 | PDGFRB 3815/4885PDGFRA 2401/4885ALDH1A1 3674/4885 |
| US-20020177606-A1 | Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them | QDPR, MRPL21, RPLP2 | PDGFRB 4560/4885PDGFRA 4124/4885ALDH1A1 1808/4885 |
| US-20070276168-A1 | Method For Preparation Of A Fluoroaromatic Compound From An Aminoaromatic Compound | DDC, NISCH, NAT1 | PDGFRB 2229/4885PDGFRA 1943/4885ALDH1A1 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.