Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19074259 | 0.81 | LMNA (0.63) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL2761472 | 0.80 | LMNA (0.61) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL426560 | 0.74 | KMT2A (0.60) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL19461035 | 0.72 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL29999168 | 0.72 | KMT2A (0.65) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| SCHEMBL4314095 | 0.71 | CYP3A4 (0.64) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| SCHEMBL26132824 | 0.71 | CYP3A4 (0.64) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| SCHEMBL13932431 | 0.71 | CYP3A4 (0.64) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| SCHEMBL10037912 | 0.71 | SMN1; SMN2 (0.64) | TSHRSMN1; SMN2LMNAHIF1AKMT2A | |
| SCHEMBL9632628 | 0.70 | SMN1; SMN2 (0.62) | TSHRSMN1; SMN2LMNAHIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288280-B1 | Production of proteins in active forms | SOUTHERN CROSS BIOTECH PTY LTD (AU) | 1995-03-08 | — | — | EP | claimed |