Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 known ✓ | P04626 | 2/20 | 0.61 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.61 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.61 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.61 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.61 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.61 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.61 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.61 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.61 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.61 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.61 |
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.61 |
| ▸ | HTR2C known ✓ | P28335 | 2/20 | 0.61 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.61 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.61 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.61 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.61 |
| ▸ | NR3C1 known ✓ | P04150 | 1/20 | 0.61 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19074259 | 0.99 | LMNA (0.63) | LMNATDP1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL29999168 | 0.93 | KMT2A (0.65) | LMNATDP1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL426560 | 0.89 | KMT2A (0.60) | LMNATDP1KMT2AALDH1A1HTT | |
| SCHEMBL26657537 | 0.81 | SMN1; SMN2 (0.67) | LMNATDP1KMT2AALDH1A1HTT | |
| SCHEMBL9157035 | 0.80 | TSHR (0.47) | LMNATDP1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL426559 | 0.78 | TSHR (0.60) | LMNATDP1KMT2AALDH1A1HTT | |
| Benzethonium SCHEMBL22711570 | 0.78 | SMN1; SMN2 (0.98) | LMNATDP1KMT2AALDH1A1HTT | |
| Benzethonium SCHEMBL1282115 | 0.78 | SMN1; SMN2 (0.98) | LMNATDP1KMT2AALDH1A1HTT | |
| Benzethonium SCHEMBL7271853 | 0.77 | SMN1; SMN2 (0.95) | LMNATDP1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL9822937 | 0.77 | SMN1; SMN2 (0.59) | LMNATDP1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351774-A1 | COMPOSITIONS CONTAINING COLOUR-NEUTRAL DEGRADABLE MICROCAPSULES | Henkel AG & Co. KGaA (DE) | 2024-04-17 | — | — | EP | disclosed |
| EP-3800184-B1 | ACETAL / KETAL-BASED FRAGRANCE AND INSECT REPELLENT PRECURSOR COMPOUNDS | HENKEL AG & CO KGAA (DE) | 2024-04-03 | — | — | EP | disclosed |
| EP-4198114-A1 | AGENTS CONTAINING EMULSIFIER AND MICROCAPSULES | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-4198113-A1 | COMPOSITIONS COMPRISING EMULSIFIER AND MICROCAPSULES | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-4198115-A1 | COMPOSITION COMPRISING EMULSIFIER AND MICROCAPSULES WITH PERFUME COMPOSITION | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| US-20230183620-A1 | AGENT CONTAINING EMULSIFIER AND MICROCAPSULES | HENKEL AG & CO. KGAA (DE) | 2023-06-15 | — | — | US | disclosed |
| WO-2022258808-A1 | COMPOSITIONS CONTAINING COLOUR-NEUTRAL DEGRADABLE MICROCAPSULES | HENKEL AG & CO. KGAA (DE) | 2022-12-15 | — | — | WO | disclosed |
| EP-4101528-A1 | COMPOSITION COMPRISING COLOUR-NEUTRAL DEGRADABLE MICROCAPSULES | Henkel AG & Co. KGaA (DE) | 2022-12-14 | — | — | EP | disclosed |
| EP-4101529-A1 | COMPOSITION COMPRISING COLOUR-NEUTRAL DEGRADABLE MICROCAPSULES WITH PERFUME COMPOSITION | Henkel AG & Co. KGaA (DE) | 2022-12-14 | — | — | EP | disclosed |
| EP-3898920-A1 | BLEACH ACTIVATORS CONTAINING TWO QUARTERNARY AMMONIUM GROUPS | Henkel AG & Co. KGaA (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2010105873-A2 | LILIAL SUBSTITUTE | HENKEL AG & CO. KGAA (DE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010105874-A1 | LILIAL SURROGATE | HENKEL AG & CO. KGAA (DE) | 2010-09-23 | — | — | WO | disclosed |
| EP-2211829-A1 | IMPROVEMENT OF THE FRAGRANCE EFFECT OF PERFUME ESTERS | Henkel AG & Co. KGaA (DE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2010084203-A1 | ADDITIONAL LAUNDRY ITEM | HENKEL AG & CO. KGAA (DE) | 2010-07-29 | — | — | WO | disclosed |
| WO-2009059858-A1 | IMPROVEMENT OF THE FRAGRANCE EFFECT OF PERFUME ESTERS | HENKEL AG & CO. KGAA (DE) | 2009-05-14 | — | — | WO | disclosed |
| WO-2008119830-A2 | FIXATING FRAGRANCES ORIGINATING FROM DETERGENTS AND CLEANING AGENTS ON HARD AND SOFT SURFACES | HENKEL AG & CO. KGAA (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2007079857-A1 | FRAGRANCE FIXING FROM WASHING AND CLEANING COMPOSITIONS TO HARD AND SOFT SURFACES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007079860-A1 | FIXING OF FRAGRANCES FROM WASHING AND CLEANING AGENTS TO HARD AND SOFT SURFACES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |
| US-5797749-A | APPLYING A MIXTURE OF BENZETHONIUM CHLORIDE, HYDROXYETHYL ACRYLATE/2-/, SODIUM FLUORIDE AND WATER TO THE CLEANED AND ACID ETCHED SURFACE OF DAMAGED TOOTH WITH EXPOSED DENTIN, WHICH PERMEATES TO THE EXPOSED SURFACE TO SEAL EXPOSED DENTIN | DANVILLE MATERIALS (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0295859-B1 | Production of proteins in active forms | SOUTHERN CROSS BIOTECH PTY LTD (AU) | 1994-11-17 | — | — | EP | disclosed |