Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017605 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017554 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017570 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9017543 | 0.90 | DHODH (0.65) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017547 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017561 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017564 | 0.90 | DHODH (0.61) | DHODHMAPTRAB9AFNTAFNTB | |
| SCHEMBL9017576 | 0.88 | DHODH (0.69) | DHODHMAPTRAB9AEPHX1ALDH1A1 | |
| SCHEMBL9017565 | 0.87 | DHODH (0.86) | DHODHFNTAFNTBEPHX2 | |
| SCHEMBL9017542 | 0.87 | DHODH (0.67) | DHODHEPHX1EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389652-A | Antiinflammatory agent | ROUSSEL-UCLAF (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5312830-A | Antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1994-05-17 | — | — | US | disclosed |