Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9426249 | 0.99 | FAAH (0.52) | FAAHMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9159580 | 0.88 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9426435 | 0.88 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL9154438 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| Hydrochloric Acid SCHEMBL9425757 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL9426865 | 0.82 | FAAH (0.58) | FAAHMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9426204 | 0.78 | KMT2A (0.47) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL9299417 | 0.75 | PPARA (0.74) | PPARAPPARGATM | |
| SCHEMBL9299418 | 0.75 | PPARA (0.74) | PPARAPPARGATM | |
| SCHEMBL9426863 | 0.74 | FAAH (0.60) | FAAHMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533516-B1 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0533516-A2 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |